In the past, women who suffered spontaneous abortions were advised to wait at least 3 months and often 6, before attempting future pregnancies. The reasoning? “To give their bodies time to heal.” The World Health Organization has recommended delaying pregnancy for 6 months after a miscarriage to achieve optimal outcomes in the next pregnancy. The professional justification was that the time was needed for the woman (and her partner) to grieve. Does delaying a pregnancy after miscarriage really help? And come to think of it, how about delaying pregnancy after an abortion? These questions beg the further question: what is the current thinking on interpregnancy intervals in general?
Oral contraceptive use was not associated with depression in a recent double-blind, randomized, placebo-controlled trial. Out of 162 women randomized to using 150 micrograms levonorgestrel and 30 micrograms ethinyl estradiol and 167 randomized to placebo pills, 7% of women in each group were moderately to severely depressed after 3 months. This study, with a strong study design is a powerful response contradicting findings an earlier and weaker study that had claimed a depression link (see the December LateBreaker “Make Me Cry: Depression Link (Again).”
“This is a big moment for women’s health,” says researcher Dr. David Goldman, of the NIH’s National Institute on Alcohol Abuse and Alcoholism. Goldman and his colleagues discovered a gene complex in women with premenstrual dysphoric disorder (PMDD). In their research, this gene complex was associated with a genetically disordered cellular response after being exposed to estrogen and progestin. Goldman hopes that what they learn about the genetic response could one day lead to improved, targeted treatment for PMDD and related disorders.
The “Contraceptive Technology” conferences will help you synthesize the data and translate the evidence into clinical “pearls” you can put directly into practice. With an array of Preconferences delving into selected specialty areas of interest, plenary sessions focusing on the “hottest” topics, a thought-provoking luncheon presentation, and 30 dynamic, interactive Concurrent Sessions, including hands-on workshops…this conference is certain to improve your clinical practice and expand your network of colleagues. Read more